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The administration of acetaminophen and codeine phosphate tablets or other opioids may obscure the analysis or medical study course in patients with acute abdominal problems.

Convey the codeine packet or leaflet inside it, any remaining medication, and every other medicines you are taking.

Use of opioids for an prolonged stretch of time might result in minimized fertility in girls and males of reproductive opportunity. It's not necessarily identified regardless of whether these effects on fertility are reversible [see Adverse Reactions].

Resulting from the risk of respiratory despair with concomitant utilization of muscle relaxants and opioids, look at prescribing naloxone to the emergency procedure of opioid overdose [see Warnings].

The concomitant use of acetaminophen and codeine phosphate tablets with all cytochrome P450 3A4 inducers or discontinuation of a cytochrome P450 3A4 inhibitor could cause lessen codeine degrees, increased norcodeine stages, and less metabolism via 2D6 with resultant reduced morphine degrees.

See disposal info at The underside of the portion for directions on how to securely toss absent (get rid of) your unused acetaminophen and codeine phosphate tablets.

Breastfeeding. Will not acquire codeine when you are breastfeeding. Codeine can move into breast milk. Tell your healthcare provider if you are breastfeeding or decide to breastfeed.

This is a lot more possible to happen If you don't Have a very gallbladder. Halt taking codeine and have emergency enable For those who have new or worse belly ache or discomfort within the upper suitable facet of your stomach-location that travels towards your again or shoulder, with or devoid of nausea and vomiting. 

You may only should choose codeine for a couple of days. Often, you might require to take it for extended. But usually, a unique drugs will probably be prescribed for prolonged-phrase suffering or diarrhoea, especially if you've got aspect effects like constipation.

Look at prescribing naloxone, according to the patient's chance aspects for overdose, including concomitant usage of other CNS depressants, a background of opioid use ailment, or prior opioid overdose. The presence of risk things for overdose mustn't reduce the correct management of pain in any presented client. Also consider prescribing naloxone If your patient has family users (including children) or other close contacts in danger for accidental ingestion or overdose. If naloxone is prescribed, educate sufferers and caregivers on how to address with naloxone [see Warnings, Habit, Abuse, and Misuse, Dangers from Concomitant Use with Benzodiazepines or Other CNS Depressants; Precautions, Information for Sufferers/Caregivers, Overdosage].

If a call is designed read more to take care of really serious respiratory melancholy from the bodily dependent affected person, administration from the antagonist ought to be begun with treatment and by titration with smaller than normal doses of your antagonist.

There are no ample and well-managed experiments in Expecting women. Codeine really should be used for the duration of pregnancy only if the likely profit justifies the possible threat.

Stay clear of the use of acetaminophen justpills and codeine phosphate tablets in adolescents twelve to eighteen decades of age who produce other risk variables that could enhance their sensitivity to the respiratory depressant effects of codeine Except if the benefits outweigh the risks.

Concentration–Efficacy Associations The minimum amount successful analgesic focus will vary extensively among individuals, In particular between people who have already been Formerly dealt with with opioid agonists.